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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TRPC6
All Species:
8.18
Human Site:
Y53
Identified Species:
20
UniProt:
Q9Y210
Number Species:
9
Phosphosite Substitution
Charge Score:
0.11
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9Y210
NP_004612.2
931
106326
Y53
A
P
L
P
C
Y
G
Y
Y
P
C
F
R
G
S
Chimpanzee
Pan troglodytes
XP_508715
931
106398
Y53
A
P
L
P
C
Y
G
Y
Y
P
C
F
R
G
S
Rhesus Macaque
Macaca mulatta
XP_001111979
862
99426
E45
T
S
L
T
A
E
E
E
R
F
L
D
S
A
E
Dog
Lupus familis
XP_546553
1099
124087
Y220
P
P
R
P
A
Y
G
Y
Y
P
C
L
Q
D
T
Cat
Felis silvestris
Mouse
Mus musculus
Q61143
930
106714
Y53
P
L
P
P
Y
G
Y
Y
P
S
F
R
G
N
E
Rat
Rattus norvegicus
Q9JMI9
836
95664
R20
P
A
F
M
F
G
A
R
G
P
S
L
T
A
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001510377
989
112393
L101
G
Y
H
P
A
G
T
L
K
C
P
L
Y
L
L
Chicken
Gallus gallus
XP_417184
895
102379
N53
Y
P
V
R
G
N
E
N
R
L
A
L
R
R
Q
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
NP_001025453
855
98053
C39
N
E
H
F
G
E
D
C
Y
G
S
Y
G
N
Y
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
P34586
1027
118084
E67
G
N
K
P
T
L
Q
E
C
L
D
Y
D
G
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
69.8
80.2
N.A.
92.8
66.8
N.A.
83.9
85.7
N.A.
70.5
N.A.
N.A.
N.A.
32.9
N.A.
Protein Similarity:
100
99.5
79.4
82.5
N.A.
95.3
77.9
N.A.
89
91
N.A.
79.4
N.A.
N.A.
N.A.
53.2
N.A.
P-Site Identity:
100
100
6.6
53.3
N.A.
13.3
6.6
N.A.
6.6
13.3
N.A.
6.6
N.A.
N.A.
N.A.
13.3
N.A.
P-Site Similarity:
100
100
6.6
66.6
N.A.
13.3
6.6
N.A.
6.6
20
N.A.
13.3
N.A.
N.A.
N.A.
20
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
20
10
0
0
30
0
10
0
0
0
10
0
0
20
0
% A
% Cys:
0
0
0
0
20
0
0
10
10
10
30
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
10
0
0
0
10
10
10
10
10
% D
% Glu:
0
10
0
0
0
20
20
20
0
0
0
0
0
0
30
% E
% Phe:
0
0
10
10
10
0
0
0
0
10
10
20
0
0
0
% F
% Gly:
20
0
0
0
20
30
30
0
10
10
0
0
20
30
0
% G
% His:
0
0
20
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
10
0
0
0
0
0
0
% K
% Leu:
0
10
30
0
0
10
0
10
0
20
10
40
0
10
10
% L
% Met:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
10
10
0
0
0
10
0
10
0
0
0
0
0
20
0
% N
% Pro:
30
40
10
60
0
0
0
0
10
40
10
0
0
0
0
% P
% Gln:
0
0
0
0
0
0
10
0
0
0
0
0
10
0
10
% Q
% Arg:
0
0
10
10
0
0
0
10
20
0
0
10
30
10
0
% R
% Ser:
0
10
0
0
0
0
0
0
0
10
20
0
10
0
20
% S
% Thr:
10
0
0
10
10
0
10
0
0
0
0
0
10
0
10
% T
% Val:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
10
10
0
0
10
30
10
40
40
0
0
20
10
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _